Lymphadenitis in Dogs

Written By hannah hollinger
Published: 02/07/2016Updated: 01/18/2022
Veterinary reviewed by Dr. Linda Simon, MVB MRCVS
Lymphadenitis in Dogs - Symptoms, Causes, Diagnosis, Treatment, Recovery, Management, Cost

What are Lymphadenitis?

Enlarged lymph nodes are generally a sign of infection. In the case of lymphadenitis, the cause is typically of a benign nature, though malignant forms are documented as well. Abnormalities and swelling of the lymph node can result in symptoms that will alert you to the fact that there is an ongoing disease present. However, it can happen that your veterinarian will find enlarged glands that you weren’t aware of during a routine examination.

Lymphadenitis is the enlargement of one or more lymph nodes in the body. The lymph nodes, or glands, increase in size in response to the influx of inflammatory cells. 

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Symptoms of Lymphadenitis in Dogs

The symptoms that you may see in your dog (in addition to these) will most likely be related to the primary disease that is causing the gland enlargement. If your dog has swollen glands, he may exhibit signs, or appear asymptomatic even if he is in pain.

  • Fever
  • Loss of appetite
  • Weight loss
  • Weakness
  • Distended abdomen
  • Coughing
  • Difficulty swallowing (dysphagia)
  • Excessive thirst (polydipsia)
  • Excessive urination (polyuria)
  • Vomiting
  • Diarrhea
  • Soft, tender nodes upon palpation

Types 

Lymphadenitis is classified depending on the extent of range in the body.

Solitary

  • A single lymph node is enlarged

Regional

  • A specific anatomical area is affected and the lymph nodes are usually interconnected

General

  • More than one area of the body is altered

It should be noted that severe lymphadenitis can extend into adjacent tissues, and can be classified as superficial or deep.

Causes of Lymphadenitis in Dogs

There are a large number of causes for lymph node inflammation, a few of which are listed here.

Infectious

Bacterial

  • Brucella canis
  • Streptococci
  • Septicemia

Rickettsial (frequently transmitted by mites, ticks)

  • Salmon poisoning
  • Ehrlichiosis

Fungal

  • Aspergillosis
  • Histoplasmosis

Parasitic

  • Toxoplasmosis
  • Babesiosis

Viral

  • Canine viral enteritides
  • Infectious canine hepatitis

Non Infectious

  • Drug reactions, immune mediated disorders like rheumatoid arthritis

Infiltrative (Neoplastic)

  • Leukemia
  • Multiple Myeloma
  • Mast Cell Tumor
  • Lymphoma

Nonneoplastic

  • Eosinophilic granuloma complex
  • Mast cell infiltration

Diagnosis of Lymphadenitis in Dogs

Part of the diagnosis of the lymph node inflammation will involve checking carefully for underlying disease processes. When you bring your furry family member to the clinic, be ready to relay as much information as possible in regards to the behavior of your dog in recent days.Your veterinary team will ask questions in order to learn more about the health status of your beloved pet.

  • Has your dog been eating well?
  • Does he have trouble swallowing?
  • Does he appear to be in pain?
  • Do you think he has lost weight?
  • Has his behavior changed (energy level, enthusiasm for regular activities)?

Your veterinarian will order a complete blood count and serum biochemistry, to look for specific markers that may point to illness or infection (hypercalcemia and hyperglobulinemia are common with lymph node inflammation). A test called polymerase chain reaction (PCR) will analyze and identify tissues. 

She may want to perform radiographs of the chest, neck, and abdomen, especially if she has been able to locate any glands that are swollen. An ultrasound can prove to be a good diagnostic tool as well since it can give a good view of organs that may be affected.

A fine needle aspirate, or needle core, partial, or excisional biopsy may be done for further investigation into the inflammatory origin.

Treatment of Lymphadenitis in Dogs

The therapy for lymphadenitis will depend on the cause. Antibiotics, antifungal medications, and anti-inflammatories will be prescribed as required. Surgery, chemotherapy and radiation in the case of neoplastic inflammation will be considered, with regular follow up appointments needed to verify if the cancer is being eradicated.

Because the root of the problem can vary extensively, your veterinarian will discuss with you the various options or therapies required to best get your pet back to a normal state of health.

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Recovery of Lymphadenitis in Dogs

The recovery of lymphadenitis will depend completely on the response that your dog’s system has to the therapy. The age of your pet, their current health status, and the underlying condition will all influence prognosis.

Always complete any medicinal prescriptions that your veterinarian has prescribed, even if your pet appears to be getting better. Keep all follow up appointments as well, because many types of lymph node inflammation need careful monitoring to assure that they are being thoroughly dealt with.

Lymphadenitis can be expensive to treat. To avoid high vet care expenses, secure pet health insurance today. The sooner you insure your pet, the more protection you’ll have from unexpected vet costs.

Lymphadenitis Average Cost

From 367 quotes ranging from $200 - $3,000

Average Cost

$1,500

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Lymphadenitis Questions and Advice from Veterinary Professionals

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Chihuahua

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Eight Years

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3 found this helpful

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3 found this helpful

My pet has the following symptoms:
Swollen Neck
My dog has been acting a little funny, lately she’s been slower, she’s been staying in one spot shaking. Her neck feels swollen and a lump. Also when i pick her up she cries like i hurt her and im just trying to make her comfortable.

Sept. 26, 2020

Answered by Dr. Michele K. DVM

3 Recommendations

Thank you for your question. She may have a problem with her neck or back,and It would be best to have your pet seen by a veterinarian, as they can examine your pet, see what might be going on, and get treatment for them if needed.

Oct. 17, 2020

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Golden Retriever

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Four Years

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0 found this helpful

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0 found this helpful

My pet has the following symptoms:
Nodes
My pet dog is female of 4.5 years. She has 7 to 8 nodes of 1 to 2 cms on her body. She is not eating well and is in a lot of pain.

Sept. 24, 2020

Answered by Dr. Michele K. DVM

0 Recommendations

Thank you for your question. I apologize for the delay, this venue is not set up for urgent emails. It would be best to have your pet seen by a veterinarian, as they can examine them, see what might be going on, and get any testing or treatment that might be needed.

Oct. 24, 2020

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Lymphadenitis Average Cost

From 367 quotes ranging from $200 - $3,000

Average Cost

$1,500

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